The experimental study of the antihypoxic properties of harmine hydrochloride

A derivative of the beta-carboline alkaloid harmine — drug hydrochloride was studied for presence antihypoxic properties in models hypobaric hypoxia and normobaric with hypercapnia. It found that does not have a signifi cant compensatory effect test At same time, small doses (2.5 5 mg/kg) has activity test, which is expressed statistically increase life expectancy animals treated drug, compared control, conditions hypoxia. According to effect, at 2.5 mg/kg be comparable reference (mexidol, 100 mg/kg).